Hormone Optimization (HRT)
Hormone Replacement Therapy
What is Hormone Optimization?
Unlike traditional hormone replacement therapy, which uses synthetic hormones, Bioidentical Hormone Replacement Therapy uses hormones that are structurally identical to the hormones naturally produced by the body. This allows for a more natural and individualized approach to hormone replacement therapy, as the hormones used are tailored to each patient’s unique needs.

Who is the Best Fit for Hormone Replacement Therapy (HRT)?
HRT is for individuals experiencing hormonal imbalances that impact daily life. You may benefit from HRT if you have:
- Menopause & Perimenopause Symptoms – Hot flashes, mood swings, and sleep issues
- Reproductive Health Concerns – PCOS, PMS, and cycle irregularities
- Chronic Fatigue & Brain Fog – Low energy, difficulty concentrating
- Muscle & Bone Health Issues – Weakness, joint pain, osteoporosis risk
- Cancer Treatment Side Effects – Hormone-related symptoms from therapies
HRT helps restore balance, improving energy, mood, metabolism, and overall well-being.

Dr. Kristen Kupeyan
Meet Dr. Kristen Kupeyan, MD – Hormone Specialist in Windsor
Dr. Kristen Kupeyan is an experienced HRT specialist who helps both women and men navigate hormone imbalances with precision and care. She offers personalized, fully online treatment plans for symptoms related to perimenopause, menopause, and low testosterone. With advanced training in bioidentical hormone replacement therapy, Dr. Kupeyan focuses on safe, evidence-based care to help restore energy, mood, sleep, and overall hormonal balance.
Learn more or start your treatment journey today by visiting Menopause Weight Method.
Dr. Kupeyan’s Fully-Online 3-Step System
Discover the 3-Step System helping menopausal women optimize their hormones and metabolism from the comfort of home. Dr. Kupeyan’s virtual program blends personalized hormone therapy HRT with evidence-based weight management strategies to address common menopause symptoms such as hot flashes, fatigue, mood changes, and menopause weight gain.
- Comprehensive Tele-Assessment – A detailed health review pinpoints your current menopause age and unique hormone profile.
- Customized Hormone Therapy Plan – Bioidentical prescriptions are shipped to you, targeting the root causes of menopause-related changes.
- Weight-Loss & Lifestyle Coaching – Ongoing online check-ins combine nutrition, activity, and continued hormone therapy adjustments to keep results on track.
All consultations, lab reviews, and follow-ups are done 100% online, so you can balance your schedule while regaining energy, trimming inches, and feeling in control of your health. Ready to start? Book your virtual consultation today and see how streamlined, expert care can transform your life.
Hormone Optimization Patient Review
HRT Benefits:
- Energy & Metabolism: Improves energy, reduces fatigue, supports metabolism, helps manage weight
- Cognitive & Mental Well-Being: Enhances mood, reduces anxiety & depression, improves sleep, reduces brain fog
- Physical Health: Supports heart health, maintains muscle strength & bone density
Client Testimonials
What Our Clients Are Saying
See what our clients have to say about our services! Click here to leave a review or see more.
I had a great experience! The Doctor and staff are welcoming and friendly. Very knowledgeable and informative! Each step of my treatment was thoroughly explained. I will definitely be going back!
E. FILIPOV
I can not recommend B At The Top more. From start to finish it was a great experience. I was not at all pressured to make a purchase like I have felt in the past at other med spas. I’m looking forward to going back.
M. SIEBERT
I’d like to thank Nicole at B at the Top Medical for the wonderful chemical peel that I had today. My skin looks and feels amazing! I will definitely be returning to try out the different procedures that they have to offer!
P. TREMBLAY
HRT for Women
Hormones do more than regulate cycles—they impact bone strength, heart health, cognitive function, and even skin elasticity. As estrogen and progesterone decline, women may notice weaker bones, drier skin, slower metabolism, and brain fog long before menopause fully sets in.
HRT for Women isn’t just about easing symptoms—it’s about long-term wellness. By restoring hormonal balance, HRT helps protect against osteoporosis, supports heart health, and keeps your mind sharp as you age.
Menopause Therapy
PCOS Therapy
PCOS affects metabolism and reproductive health, leading to irregular cycles, weight gain, acne, and fertility challenges. HRT helps regulate hormone levels to improve symptoms and support overall well-being.
Thyroid Conditions Treatment
Thyroid disorders like hypothyroidism can cause weight gain, fatigue, and brain fog. When thyroid function declines, it disrupts metabolism and energy production. HRT can complement thyroid therapy by supporting overall hormonal balance.
Adrenal Fatigue Therapy
Chronic stress can lead to adrenal dysfunction, causing exhaustion, sleep disturbances, and difficulty handling stress.
Perimenopause Therapy
Perimenopause is the phase before menopause where hormone levels fluctuate unpredictably, causing irregular cycles, fatigue, anxiety, and insomnia. Perimenopause therapy with HRT stabilizes these fluctuations for better symptom control.
Estrogen Dominance Therapy
When estrogen levels are too high relative to progesterone, symptoms like heavy periods, bloating, mood swings, and weight gain can occur. HRT helps restore hormonal balance to reduce discomfort.
Osteoporosis Prevention Treatment
Osteoporosis weakens bones and increases the risk of fractures, often due to declining estrogen levels. HRT helps maintain bone density and strength, reducing long-term risks.
Fibromyalgia Treatment
Fibromyalgia causes chronic pain, muscle stiffness, and fatigue, and research suggests hormone imbalances may contribute to symptoms. HRT helps manage pain, improve sleep, and restore energy levels.
Conditions Treated for Women
Fatigue & Low Energy
Thyroid, progesterone, and DHEA imbalances contribute to chronic fatigue. HRT helps boost energy and restore vitality.
Low Libido & Sexual Health
Testosterone and estrogen imbalances can reduce arousal and satisfaction. HRT helps restore libido and sexual function.
Urinary Incontinence
Lower estrogen weakens pelvic floor muscles, leading to leakage. HRT helps restore tissue strength and bladder control.
Memory Loss & Brain Fog
Estrogen and thyroid hormones play a crucial role in cognitive function. HRT supports memory, focus, and mental sharpness.
Weight Gain
Hormonal imbalances—especially in estrogen, thyroid hormones, and DHEA—can slow metabolism and promote fat storage. HRT helps regulate weight by restoring balance.
Vaginal Dryness
Low estrogen reduces natural lubrication, causing discomfort and irritation. HRT helps restore moisture and improves vaginal health.
Hot Flashes & Night Sweats
Caused by declining estrogen levels, hot flashes disrupt daily life and sleep. HRT stabilizes hormone levels to reduce frequency and severity.
Mood Swings & Anxiety
Fluctuating estrogen and progesterone levels can cause emotional instability. HRT helps balance hormones for better mood regulation.
Insomnia & Sleep Disorders
Progesterone promotes relaxation, while estrogen regulates sleep cycles. HRT supports deeper, more restful sleep.
Premenstrual Syndrome (PMS)
Progesterone and estrogen imbalances lead to bloating, cramps, and irritability. HRT helps regulate cycles and ease PMS symptoms.
Uterine Fibroids
High estrogen levels can contribute to fibroid growth. HRT helps balance hormones to manage symptoms and slow progression.
Depression
Drops in estrogen, progesterone, and thyroid hormones can contribute to mood disorders. HRT helps stabilize emotions and improve mental well-being.
Osteoporosis & Bone Health
Declining estrogen weakens bones, increasing fracture risk. HRT helps maintain bone density and supports long-term skeletal health.
Dry Skin, Hair Loss, & Brittle Nails
Declining estrogen weakens bones, increasing fracture risk. HRT helps maintain bone density and supports long-term skeletal health.
Endometriosis
Excess estrogen can worsen endometrial tissue growth, causing pain and inflammation. HRT helps manage estrogen dominance and reduce discomfort.
Symptoms of Hormone Imbalance in Women:
Estrogen (Estradiol, Estriol)
Estrogen regulates menstrual cycles, bone health, and skin elasticity. HRT helps maintain balance, reducing symptoms like hot flashes, vaginal dryness, and osteoporosis risk.
Testosterone
Though often associated with men, women also need testosterone for energy, muscle tone, and libido. HRT helps restore low levels to improve strength, mood, and sexual health.
Progesterone
Progesterone supports mood, sleep, and reproductive health. HRT helps ease anxiety, insomnia, and irregular cycles while balancing estrogen levels.
DHEA
DHEA is a precursor to testosterone and estrogen, playing a role in energy, metabolism, and immune health. HRT helps combat fatigue, low libido, and brain fog.
Perimenopause Therapy
Perimenopause is the phase before menopause where hormone levels fluctuate unpredictably, causing irregular cycles, fatigue, anxiety, and insomnia. Perimenopause therapy, HRT stabilizes these fluctuations for better symptom control.
Thyroid Hormones
Essential for metabolism, energy, and mental clarity. HRT supports thyroid function to reduce fatigue, weight gain, and cognitive fog.
HRT Hormones We Use for Women
HRT for Men
Hormones play a critical role in energy, strength, mental clarity, and overall vitality. As men age, testosterone and other key hormones naturally decline, often leading to subtle but significant changes in muscle mass, metabolism, and cognitive function long before symptoms become obvious.
HRT for Men isn’t just about restoring testosterone—it’s about long-term wellness. By optimizing hormone balance, HRT supports heart health, maintains muscle strength, sharpens focus, and improves overall quality of life as you age.
Andropause Therapy (Male Menopause)
As testosterone declines with age, men experience fatigue, weight gain, mood swings, and reduced libido. Andropause therapy restores hormonal balance, helping improve energy, confidence, and overall well-being.
Erectile Dysfunction Therapy
Testosterone and other hormones play a critical role in blood flow and sexual function. Erectile dysfunction therapy helps restore natural testosterone levels, improving arousal, stamina, and overall performance.
Thyroid Imbalance Treatment
An underactive thyroid can slow metabolism, cause weight gain, and lead to brain fog. This therapy restores thyroid hormones (T3 & T4) to improve energy, metabolism, and mental clarity.
Low Testosterone Therapy (Low T)
Low libido, fatigue, reduced muscle mass, mood changes, and erectile dysfunction.
Estrogen Dominance Therapy
When estrogen levels are too high relative to progesterone, symptoms like gynecomastia, weight gain, and low libido may occur. HRT helps restore hormonal balance to reduce discomfort.
Fibromyalgia Treatment
Fibromyalgia causes chronic pain, muscle stiffness, and fatigue, and research suggests hormone imbalances may contribute to symptoms. HRT helps manage pain, improve sleep, and restore energy levels.
Conditions Treated for Men
Difficulty Building Muscle & Strength Loss
Low Libido & Reduced Sexual Performance
Low testosterone is a major cause of decreased sex drive and performance issues. HRT helps restore healthy libido and sexual function.
Memory Loss & Brain Fog
Hormonal imbalances can slow mental clarity, focus, and memory. HRT helps improve cognitive function and alertness.
Dry Skin & Decreased Collagen Production
Low testosterone and DHEA can reduce skin hydration and elasticity, leading to dry skin and early aging. HRT helps restore skin vitality.
Poor Exercise Recovery
Struggling with longer recovery times and lingering soreness? Low testosterone and growth hormone may be affecting your muscle repair and endurance.
Erectile Dysfunction
Hormones regulate blood flow and arousal. Low testosterone can contribute to ED and decreased stamina. HRT supports better circulation and performance.
Depression & Irritability
Low testosterone can lead to mood swings, low motivation, and depression. HRT supports emotional stability and mental well-being.
Hair Thinning & Loss
Testosterone imbalances can cause hair loss and thinning, affecting scalp and facial hair growth. HRT helps slow hair loss and promote regrowth.
Weight Gain & Slower Metabolism
Testosterone and thyroid hormones regulate fat distribution and metabolism. When levels drop, it’s easier to gain weight—especially around the abdomen.
Reduced Sperm Count & Fertility Issues
Testosterone is crucial for sperm production and reproductive health. Low levels can affect fertility and hormone balance. HRT can help optimize function.
Mood Swings & Anxiety
Imbalanced hormones may cause sudden mood changes, anxiety, and stress. HRT helps stabilize mood and promote mental clarity.
High Blood Pressure
Testosterone and thyroid hormones help regulate heart health and circulation. Low levels can lead to high blood pressure and poor vascular function.
Osteoporosis & Bone Health
Men can lose bone density with low testosterone, increasing the risk of fractures and joint pain. HRT helps maintain bone strength and stability.
Testicular Shrinkage
Low testosterone may reduce testicle size and function, impacting fertility and hormone levels. HRT helps maintain healthy testosterone production.
Fatigue & Low Energy
Feeling constantly tired and unmotivated? Low testosterone and adrenal dysfunction may be draining your energy and stamina.
Hot Flashes & Night Sweats
Yes, men can experience hot flashes too, often due to low testosterone or adrenal issues. HRT helps regulate body temperature and comfort.
Joint Pain & Stiffness
Hormonal imbalances can lead to inflammation and joint stiffness, making daily movement harder. HRT helps support joint function and flexibility.
Gynecomastia
Imbalanced testosterone and estrogen can cause male breast tissue enlargement. HRT helps restore proper hormone levels for a balanced body.
Urinary Incontinence
Hormonal changes can weaken bladder control, causing frequent urges or leakage. HRT supports better urinary function and muscle strength.
Symptoms of Hormone Imbalance in Men:
Testosterone
Testosterone is the key hormone for male health, affecting muscle strength, libido, energy levels, and mental clarity. Low levels can lead to fatigue, weight gain, mood swings, and erectile dysfunction. HRT helps restore testosterone for better vitality and performance.
Progesterone
Often called the “brain hormone,” Pregnenolone plays a role in memory, focus, and stress resilience. It also contributes to testosterone and DHEA production, supporting hormonal balance and mental clarity.
DHEA
DHEA is a precursor to testosterone, helping with energy, muscle recovery, and stress management. Low DHEA levels are linked to fatigue, brain fog, and reduced endurance. HRT helps optimize DHEA levels to support overall well-being.
Growth Hormone - HGH
HGH supports muscle repair, fat loss, and anti-aging benefits. As HGH declines, men experience slower recovery, weaker muscles, and increased body fat. HRT helps restore HGH for improved physical performance and longevity.
Thyroid Hormones
Thyroid hormones control metabolism, energy, and brain function. If your thyroid is underactive, you may experience weight gain, sluggishness, and difficulty concentrating. HRT helps regulate thyroid hormones for better metabolic and cognitive health.
HRT Hormones We Use for Men
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Get in Touch
For general inquiries please fill out the form below or simply call: 519-915-4514. We also offer direct online booking.
Hormone Delivery Methods for Men & Women:
Pellets
Small implants placed under the skin, slowly releasing hormones for 3–6 months. Provides steady levels with no daily maintenance. Most common for testosterone, estrogen, and progesterone.
Injections
Typically given weekly or biweekly for testosterone, estrogen, or DHEA.
Gels & Creams
Applied to the skin daily, absorbed into the bloodstream. Common for testosterone, estrogen, and progesterone
Patches
Adhesive patch worn on the skin, replaced every few days. Provides steady hormone release for estrogen therapy.
Oral Capsules & Tablets
Traditional pill format, processed through the liver. Used for progesterone, DHEA, and thyroid hormones
Nasal & Vaginal Applications
Nasal spray for testosterone and DHEA. Vaginal creams, rings, or tablets for localized estrogen therapy.Helps with vaginal dryness and urinary symptoms.
Troches and Sublingual Tablets
Dissolve under the tongue, providing fast absorption. Used for estrogen, progesterone, and testosterone.
Frequently Asked Questions

How long does it take to see HRT results?
As one of our patients mentioned in the video, it took her 1 month to see results. It can sometimes take 2 months to see results depending on the treatment and journey you’re on.
What is Hormone Replacement Therapy (HRT)?
HRT is a treatment that uses hormones that are identical on a molecular level to the natural hormones found in the human body. It’s designed to address imbalances in the body’s hormone levels.
How is HRT different from traditional hormone replacement therapy?
Unlike traditional hormone therapies that use synthetic or animal-derived hormones, HRT uses hormones derived from plant sources that are biologically identical to those produced by the human body.
How is the dosage determined for HRT?
Dosage is typically determined based on individual hormone testing, symptoms, medical history, and other factors. It’s personalized to meet the specific needs of each patient. Our doctors will complete all necessary assessments to ensure a healthy journey.
Can men also benefit from HRT?
Yes, HRT is not just for women. Men experiencing symptoms related to testosterone decline or other hormonal imbalances can also benefit from HRT.
What are the symptoms/conditions of hormone imbalance?
- Muscle or Bone Density Reduction
- Feelings of Despondency
- Frequent Mood Shifts
- Struggling with Weight Management
- Skin Breakouts
- Persistent Tiredness
- Challenges with Sleep Patterns
- Forgetfulness Episodes
- Brain Fog and Concentration Issues
- Joint Discomfort and Rigidity
- Migraines and Regular Headaches
- Episodes of Anxiety and Panic
- Heartbeat Irregularities
- Overactive Sweat Glands
- Water Retention and Bloating
- Signs of Skin Aging
- Concerns with Thyroid Function
- Thinning or Hair Loss
- Unusual Hair Growth Patterns
- Reduced Bone Strength
- History of Multiple Miscarriages
- Presence of Uterine Fibroids
- Endometrial Complications
- Tenderness in Breasts Due to Fibrocystic Changes
What is perimenopause, and how is it different from menopause?
Perimenopause is the transition leading up to menopause when estrogen and progesterone levels fluctuate. Periods become irregular, but haven’t stopped for 12 consecutive months (that’s when menopause is confirmed). Common symptoms can include hot flashes, night sweats, sleep or mood changes, brain fog, and vaginal dryness. The transition typically starts in the 40s (earlier or later for some) and can last several years.
Can HRT be used during perimenopause to help manage symptoms?
For appropriate candidates, HRT may help ease bothersome perimenopausal symptoms by supplementing hormones that are changing. Suitability is determined during a clinical consultation with our experts that reviews your medical history, risk factors, current cycle pattern, symptom goals, and—when indicated—lab testing. If started, dosing is individualized and monitored over time.